OSCOAT Polymers are available in a wide range of different physical forms aqueous dispersion, organic solution, granules and powders. The basis of our offerings is our Poly (meth) acrylates for pharmaceutical applications. The range of our product portfolio provides full flexibility for your targeted drug release profiles by offering best performance for enteric, protective or sustained-release properties. OSCOAT polymers are copolymers derived from esters of acrylic and methacrylic acid.

If you need to protect your active from the gastric fluid and would like to improve drug effectiveness OSCOAT L-100 and S-100 polymers are your preferred choice of coating polymers. They enable targeting specific areas of the intestine. In addition, the different grades can be combined with each other, making it possible to adjust the dissolution pH, and thus to achieve the required GI targeting for the drug. Targeted drug release in the colon is required for local treatment of intestinal disorders such as Crohn’s disease, ulcerative colitis or intestinal cancer.

Sustained intestine delivery of drugs was developed that could bypass the stomach and release the loaded drug for long periods into the intestine by coating of OSCOAT polymer. OSCOAT L-100 & OSCOAT S-100 are two forms of commercially available enteric acrylic resins. Both of them produce films resistant to gastric fluid. OSCOAT L & S are soluble in intestinal fluid at pH 6 & 7 respectively. OSCOAT L-100 is dissolution behavior in 0.1 N HCl for two hours and then media was changed to phosphate buffer pH 6.8.

Colonic drug delivery is a relatively recent approach for the treatment of diseases like ulcerative colitis, Crohn’s disease, and irritable bowel syndrome. PH-sensitive polymers that dissolve, or above pH 7 used for colonic drug delivery. Whereas OSCOAT L 100 and S100 mixture (1:1, 1:2, and 1:3) were used.

The preferred coating is OSCOAT FS 30 D, which combines release in the colon with the following technical advantages:

• aqueous processing
• highly flexible coatings
• suitable for multiparticulate tablet preparation.

The mechanical properties of casted OSCOAT E-100 films were tested for the combined effect of two cohesion promoters (succinic or citric acid) and triacetin as a plasticizer. The prepared films were elastic, self-adhesive, transparent and pale yellow in color. OSCOAT E100 polymer was found to result in wrinkle-free transparent films with good adhesion to skin. OSCOAT E100 polymer, and 100% release was observed within 20 minutes

Needed to improve film elasticity Recommended Plasticizers – Triethyl Citrate, Castor Oil, Propylene glycol, Polyethylene Glycol, Di Ethyl phthalate, Triacetin, Dibutyl sebacate etc. 

Powder form: 5kg and 25kg net in PP Drum with polyethylene liner. Liquid form: 60kg plastic drum.  Liquid Form: 35 Kg Plastic Carboys

Powder store at dry place below 25 C Temp. Liquid: Store at dry place between 5 -35 C.

 As OSCOAT range is a high molecular weight polymer, it cannot be absorbed by body. Thus, it is safe for human consumption

Powder form: Five years from date of manufacturing in intact condition. Liquid form 2 Years.